产品货号:
Z30634
中文名称:
CCR5抗体
英文名称:
Anti-CCR5 Antibody
产品规格:
100μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-CCR5 Antibody |
指标别名 | C C chemokine receptor type 5;C C CKR 5;CC CKR 5;CCCKR5;CCR 5;CCR5;CD195;CHEMR13;CKR 5;CKR5;CMKBR5;HIV 1 fusion coreceptor;IDDM22 |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | IHC,ELISA |
基因名称 | CCR5 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | Synthesized peptide derived from human CKR-5 around the non-phosphorylation site of S336. |
计算分子量 | 41KD |
成分 | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
纯化方式 | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | -20℃可保存1年,短期保存或频繁使用请置于4℃,可保存一个月,避免反复冻融。 |
背景资料 | C-C chemokine receptor type 5,also known as CCR5 or CD195,is a protein on the surface of white blood cells that is involved in the immune system as it acts as a receptor for chemokines.It is mapped to 3p21.31.This gene encodes a member of the beta chemokine receptor family,which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors.This protein is expressed by T cells and macrophages,and is known to be an important co-receptor for macrophage-tropic virus,including HIV,to enter host cells.Defective alleles of this gene have been associated with the HIV infection resistance.The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2),macrophage inflammatory protein 1 alpha (MIP-1 alpha),macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES).Expression of this gene was also detected in a promyeloblastic cell line,suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation.This gene is located at the chemokine receptor gene cluster region.An allelic polymorphism in this gene results in both functional and non-functional alleles;the reference genome represents the functional allele.Two transcript variants encoding the same protein have been found for this gene. |
Uniprot ID | P51681 |
基因名全称 | C-C chemokine receptor type 5 |
蛋白名全称 | C-C chemokine receptor type 5 |
推荐稀释比 | IHC 1:100~1:300 ELISA 1:5000 |
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